The Spotreducer cream contains the following active ingredients:
Vitamin B3 (niacinamide, nicotinamide)
As an essential nutrient, vitamin B3 plays an important role in cellular energy production and is important for overall skin care. It helps to lighten pigmentation and age spots and vitamin B3 works against both the yellowing of the skin and blotchiness. Vitamin B3 has anti-inflammatory properties and is an important supplementary ingredient in the treatment of troubled skin. More about: Niacinamide an active substance, countless positive effects
Vitamin B3 does not inhibit the direct production of melanin (skin pigment), but stops up to 68% the transport of melanosomes (organ in a skin cell that stores pigment in a package) to the surrounding keratinocytes (skin cells). A clinical study showed that after applying a cream containing vitamin B3 for 8 weeks, the skin gradually became lighter. The age spots around the eyes and on the cheeks were reduced. More about pigment and in particular about melanocytes (pigment cell), melanosomes (pigment package)
Double-blind randomized study (Niacinamide versus Hydroquinone in patients with pregnancy mask) from 2011 concluded: Niacinamide reduced dark spots, inflammatory response and solar elastosis (= loss of your elastic structure in the dermis) and is a safe and effective.
More about pigment spots after a skin condition
By preventing both moisture loss and dryness, vitamin B3 provides a good skin barrier, which prevents the loss of water without feeling heavy and greasy. When assessed for transepidermal water loss (TEWL), a 2000 study found that just 2% of vitamin B3 reduced TEWL by 24% in just 4 weeks. At the same time, the essential fatty acids and the ceramides (the natural lipids in the epidermis that protect against moisture loss and against bacteria) were increased by 67% and 34% respectively.
Skin resistance and sun damage reduction:
An Australian study showed a reduction in actinic keratosis (precursor to a skin cancer, squamous cell carcinoma) after using niacinamide 1% cream. In addition, niacinamide prevents the suppression of the immune system provoked by ultraviolet A (UVA) and B (UVB) rays. Ultraviolet A is always present during all hours of daylight, regardless of cloud cover, snow, rain or storm.
Discovered in the deserts and salt lakes of Egypt, ectoine is a natural substance that protects microorganisms against dehydration, UVA and UVB radiation and extreme temperatures. A study conducted on more than 100 women confirmed that ectoine not only reduces wrinkles, but also prevents the formation of new wrinkles. In addition, ectoine supports the skin’s repair mechanisms against UV damage, limiting premature photo-aging. Ectoin also binds water molecules making the skin feel smoother and more supple.
Aqua, Caprylic/Capric Triglyceride, Niacinamide, Rosa Damascena Flower Water*, Cetearyl Alcohol, Butyrospermum Parkii Butter*, Cetyl Palmitate, Cocos Nucifera Oil*, Ectoin, Glyceryl Stearate, Prunus Amygdalus Dulcis Oil*, Glycerin, Simmondsia Chinensis Seed Oil*, Sodium Cetearyl Sulfate, Parfum, Porphyra Umbilicalis Extract, Ascorbyl Palmitate, Tocopherol, Algin, Sodium Benzoate, Phytic Acid, Helianthus Annuus Seed Oil, Sodium Lactate, Lactic Acid
Conserved with Sodium Benzoate
Content 30 cc
Reduce early signs of dark spots in the skin, skin regeneration to limit UV damage and shrink pores. Suitable for all skin types.
What we care about:
1.Bissett DL, Miyamoto K, Sun P, Li J, Berge CA. Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin. Int J Cosmet Sci. 2004;26:231-8.
2.Levin J, Momin SB. How much do we really know about our favorite cosmeceutical ingredients? J Clin Aesthet Dermatol. 2010;3:22-41.
3.Tanno O, Ota Y, Kitamura N, Katsube T, Inoue S. Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier. Br J Dermatol. 2000;143:524-31.
4.Marini A, Reinelt K, Krutmann J, Bilstein A. Ectoine-containing cream in the treatment of mild to moderate atopic dermatitis: a randomised,comparator-controlled, intra-individual double-blind, multi-center trial. Skin Pharmacol Physiol. 2014;27:57-65.
5. Graf R, Anzali S, Buenger J, Pfluecker F, Driller H. The multifunctional role of ectoine as a natural cell protectant. Clin Dermatol. 2008;26:326-33.
6: Heinrich U, Garbe B, Tronnier H. In vivo assessment of Ectoin: a randomized, vehicle-controlled clinical trial. Skin Pharmacol Physiol. 2007;20:211-8.
7. Buenger J, Driller H. Ectoin: an effective natural substance to prevent UVA-induced premature photoaging. Skin Pharmacol Physiol. 2004;17:232-7.
8. A Double-Blind, Randomized Clinical Trial of Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma. Navarrete-Solís J, Castanedo-Cázares JP, Torres-Álvarez B, Oros-Ovalle C, Fuentes-Ahumada C, González FJ, Martínez-Ramírez JD, Moncada B. Dermatol Res Pract. 2011:379173.
9. Moloney F, Vestergaard M, Radojkovic B, Damian D. Randomized, double-blinded, placebo controlled study to assess the effect of topical 1% nicotinamide on actinic keratoses. Br J Dermatol. 2010;162:1138-9.
10. Damian DL, Patterson CR, Stapelberg M, Park J, Barnetson RS, Halliday GM. UV radiation-induced immunosuppression is greater in men and prevented by topical nicotinamide. J Invest Dermatol. 2008;128:447-54.
11. Hakozaki T, Minwalla L, Zhuang J, Chhoa M, Matsubara A, Miyamoto K, Greatens A, Hillebrand GG, Bissett DL, Boissy RE. The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. Br J Dermatol. 2002 Jul;147(1):20-31.
Ask your dermatologist
What is the difference between Iconic Elements Spot Reducer and Targeted Pigment Serum? Targeted Pigment serum focuses more on reducing pigment spots due to its triple effect. In addition to reducing spots (pigment, spots and spots), Spot Reducer also has a moisturizing effect due to the addition of Ectoine.
I have sensitive skin, can I use both Spotreducer and Targeted Pigment serum?You can use Spot Reducer without any problems. Targeted Pigment can cause skin irritation in people with sensitive skin. Malic Acid (malic acid) an exfoliant, gives a light skin peeling, to renew the skin cells faster. Due to the accelerated skin renewal, the pigment spots disappear faster. This can cause skin irritation in people with sensitive skin.
Can you use Spot Reducer and Targeted Pigment serum in combination? Yes, that’s possible. The products are formulated in such a way that they can be used side by side. First apply the Targeted Pigment serum, let it soak in for a short while and then apply Spotreducer cream.